Isaac Pepper was born in the mid-1700s. He married Elizabeth Freeman.

Mercy Pepper, daughter of Isaac Pepper and Elizabeth Freeman, was born August 07, 1690, in Eastham, Barnstable, MA. She marrried William Freeman on October 16, 1711, in Eastham, Barnstable, MA. Mercy died October 09, 1769, in Harwich, Barnstable, MA.